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CBD Oil Side Effects - Do They Exist?

Thursday, 28 March 2019

If you've done some reading about CBD online you'll likely have heard one phrase repeated again and again: "CBD is both safe and well tolerated." These are the words of the World Health Organisation (WHO) and they hold more authority than the online enthusiasts generally repeating them.

We could leave this question there – and in almost all cases it says as much as you need to know – but since CBD does have effects there are also some (obscure) situations in which you might encounter CBD Oil side effects.

What Are The CBD Oil Side Effects?

Can You Take Too Much CBD?

For most users CBD has no negative side effects, particularly at the kinds of doses that are available for purchase in the UK. It is, however, possible to take too much CBD, just as it is possible to consume too much of most things.

The good news is that taking too much CBD is not serious and will at most result in a headache, nausea or drowsiness. In this respect it is not dissimilar to chamomile tea! 

It's All in the Oil

Many complaints about these sorts of effects have less to do with CBD than the oil in which it is suspended. It is always worth examining the other ingredients in CBD oil (there shouldn't be many!) to make sure you won't have an adverse reaction them. If you do find a specific oil doesn't sit well with you, there are plenty of different oils for you to try from.

All our CBD Oil products feature full ingredient listings for your ease of mind.

The Research

A 2017 literature review of the work carried out on CBD has found that "the often described favourable safety profile of CBD in humans was confirmed and extended by the reviewed research." It also reported that side effects for CBD have generally only been found in micro-organisms and animals.

Does CBD Interact with Any Drugs or Medications?

Since CBD has only recently risen to prominence, there is a great deal of work that still needs to be done on its interactions with other substances. The singular piece of advice to give is that you should consult your doctor if you are concerned CBD could have an adverse interaction with your medication regimen. 

While CBD has consistently been found safe for use, there is some evidence that it can inhibit the cytochrome P450 enzyme system in the liver. Still, in the vast majority of cases this not a cause for concern. 

What Is the Cytochrome P450 Enzyme System?

The P450 system is responsible for the metabolism of around 60% of the potentially toxic chemicals you ingest. This means that when taken alongside CBD certain drugs will not be metabolised in the manner expected by doctors, and could have more significant impacts on the body than expected: in practical terms potentially increasing the dose of medication. This is the same reason your doctor may have advised you not to drink grapefruit juice while on certain medications, and is not a cause for concern outside a small set of situations.


We make no medical claims about CBD, and any advice on its potential interaction with medication should be sought directly from your doctor.

More Common CBD Questions

If you would like to try out CBD, please take a look at out guide to the Best Way to Take CBD or browse our Full CBD Selection.

Do you have any questions about our CBD products? Please don't hesitate to let us know in the comments, or find us on Facebook and Twitter.

Tags: General Health, CBD

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